MovDisordV3, Main, Exploration, bibRecord, 005802

n‐Hexane‐induced parkinsonism: Pathogenetic hypotheses

Identifieur interne : 005802 ( Main/Exploration ); précédent : 005801; suivant : 005803

n‐Hexane‐induced parkinsonism: Pathogenetic hypotheses

Auteurs : Pezzoli [Italie] ; A. Antonini [Suisse] ; S. Barbieri [Italie] ; M. Canesi [Italie] ; L. Perbellini [Italie] ; A. Zecchinelli [Italie] ; C. B. Mariani [Italie] ; A. Bonetti [Italie] ; K. L. Leenders [Suisse]

Source :

Movement Disorders [ 0885-3185 ] ; 1995-05.

RBID : ISTEX:0A6367FCB24CFEFCD01FEBEF0E29EAF8D96CECD2

English descriptors

KwdEn :
- 2, 5‐Hexanedione, Air Pollutants, Occupational (adverse effects), Blood Glucose (metabolism), Brain (drug effects), Brain (radionuclide imaging), Brain Mapping, Corpus Striatum (drug effects), Corpus Striatum (radionuclide imaging), Hexanes (adverse effects), Humans, Hydrocarbons, Lipid Peroxidation (drug effects), Lipid Peroxidation (physiology), Lipid peroxidation, Male, Middle Aged, Neurologic Examination (drug effects), Occupational Diseases (chemically induced), Occupational Diseases (radionuclide imaging), Parkinson Disease, Secondary (chemically induced), Parkinson Disease, Secondary (radionuclide imaging), Parkinson's disease, Positron emission tomography, Receptors, Dopamine (drug effects), Receptors, Dopamine (physiology), Substantia Nigra (drug effects), Substantia Nigra (radionuclide imaging), Tanning, Tomography, Emission-Computed, n‐Hexane.
MESH :
- chemical , adverse effects : Air Pollutants, Occupational, Hexanes.
- chemical , drug effects : Receptors, Dopamine.
- chemical , metabolism : Blood Glucose.
- chemically induced : Occupational Diseases, Parkinson Disease, Secondary.
- drug effects : Brain, Corpus Striatum, Lipid Peroxidation, Neurologic Examination, Substantia Nigra.
- physiology : Lipid Peroxidation, Receptors, Dopamine.
- radionuclide imaging : Brain, Corpus Striatum, Occupational Diseases, Parkinson Disease, Secondary, Substantia Nigra.
- Brain Mapping, Humans, Male, Middle Aged, Tanning, Tomography, Emission-Computed.

Abstract

n‐Hexane, similar hydrocarbons, and derivatives are common environmental pollutants and by‐products of lipid peroxidation, and they may have a nigrotoxic effect like that of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine. This report describes our second case of parkinsonism in a subject exposed to n‐hexane. Positron emission tomography studies demonstrated regional striatal abnormalities of the nigrostriatal dopaminergic system and of glucose metabolism that were different from those found in idiopathic Parkinson's disease.

Url:

https://api.istex.fr/document/0A6367FCB24CFEFCD01FEBEF0E29EAF8D96CECD2/fulltext/pdf

DOI: 10.1002/mds.870100308

Affiliations:

Le document en format XML

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<author><name sortKey="Pezzoli" sort="Pezzoli" uniqKey="Pezzoli" last="Pezzoli">Pezzoli</name>
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<author><name sortKey="Antonini, A" sort="Antonini, A" uniqKey="Antonini A" first="A." last="Antonini">A. Antonini</name>
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<author><name sortKey="Barbieri, S" sort="Barbieri, S" uniqKey="Barbieri S" first="S." last="Barbieri">S. Barbieri</name>
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<author><name sortKey="Canesi, M" sort="Canesi, M" uniqKey="Canesi M" first="M." last="Canesi">M. Canesi</name>
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<author><name sortKey="Perbellini, L" sort="Perbellini, L" uniqKey="Perbellini L" first="L." last="Perbellini">L. Perbellini</name>
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<author><name sortKey="Zecchinelli, A" sort="Zecchinelli, A" uniqKey="Zecchinelli A" first="A." last="Zecchinelli">A. Zecchinelli</name>
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<author><name sortKey="Mariani, C B" sort="Mariani, C B" uniqKey="Mariani C" first="C. B." last="Mariani">C. B. Mariani</name>
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<author><name sortKey="Bonetti, A" sort="Bonetti, A" uniqKey="Bonetti A" first="A." last="Bonetti">A. Bonetti</name>
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<term>Brain (drug effects)</term>
<term>Brain (radionuclide imaging)</term>
<term>Brain Mapping</term>
<term>Corpus Striatum (drug effects)</term>
<term>Corpus Striatum (radionuclide imaging)</term>
<term>Hexanes (adverse effects)</term>
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<front><div type="abstract" xml:lang="en">n‐Hexane, similar hydrocarbons, and derivatives are common environmental pollutants and by‐products of lipid peroxidation, and they may have a nigrotoxic effect like that of 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐tetrahydropyridine. This report describes our second case of parkinsonism in a subject exposed to n‐hexane. Positron emission tomography studies demonstrated regional striatal abnormalities of the nigrostriatal dopaminergic system and of glucose metabolism that were different from those found in idiopathic Parkinson's disease.</div>
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Movement Disorders (revue)

n‐Hexane‐induced parkinsonism: Pathogenetic hypotheses

n‐Hexane‐induced parkinsonism: Pathogenetic hypotheses

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English descriptors

Abstract

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	Movement Disorders (revue)
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